The Franciscan padres used
Encino as their headquarters while exploring the valley
before establishing Mission San Fernando in 1797. In 1849
Vincente de la Osa built an adobe with nine rooms. The
next owner of El Encino Rancho was Eugene Garnier, who
built the existing two-story limestone house in 1872.
In December 1891 Domingo Amestoy acquired the property.